| Strain-promoted double-click reaction for chemical modification of azido-biomolecules. | |
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MedLine Citation:
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PMID: 20657923 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The strain-promoted "double-click" (SPDC) reaction using Sondheimer diyne, a novel convergent method conjugating three molecules spontaneously, has enabled us to readily modify an azido-biomolecule with a small reporter azido-molecule. |
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Authors:
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Isao Kii; Akira Shiraishi; Toshiyuki Hiramatsu; Takeshi Matsushita; Hidehiro Uekusa; Suguru Yoshida; Makoto Yamamoto; Akira Kudo; Masatoshi Hagiwara; Takamitsu Hosoya |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-26 |
Journal Detail:
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Title: Organic & biomolecular chemistry Volume: 8 ISSN: 1477-0539 ISO Abbreviation: Org. Biomol. Chem. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-26 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: England |
Other Details:
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Languages: eng Pagination: 4051-5 Citation Subset: IM |
Affiliation:
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Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. ikii@bio.titech.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Azides
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chemistry* Carbohydrates / chemistry* Cell Line Click Chemistry / methods* Computer Simulation Crystallography, X-Ray Fluorescent Dyes / chemistry* Humans Lipids / chemistry* Models, Molecular Molecular Structure Nucleotides / chemistry* Proteins / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Azides; 0/Carbohydrates; 0/Fluorescent Dyes; 0/Lipids; 0/Nucleotides; 0/Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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