Document Detail


Straightforward approach to efficient oxidative DNA cleaving agents based on Cu(ii) complexes of heterosubstituted cyclens.
MedLine Citation:
PMID:  23412684     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Cu(ii) complexes of cyclen and two of its heterosubstituted analogues were shown to be efficient oxidative DNA cleavers. The reactivity strongly depends on the heteroatom inserted into the macrocycle (O > S > N).
Authors:
Jan Hormann; Chrischani Perera; Naina Deibel; Dieter Lentz; Biprajit Sarkar; Nora Kulak
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-15
Journal Detail:
Title:  Dalton transactions (Cambridge, England : 2003)     Volume:  -     ISSN:  1477-9234     ISO Abbreviation:  Dalton Trans     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101176026     Medline TA:  Dalton Trans     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, D-14195 Berlin, Germany. nora.kulak@fu-berlin.de.
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