| Strabismus in the Marfan syndrome. | |
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MedLine Citation:
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PMID: 8172269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied 573 patients with the Marfan syndrome for the presence of ocular misalignment, refractive errors, and amblyopia. A total of 110 patients (19.2%) had strabismus. Of 573 patients, exotropia occurred in 67 (11.7%), esotropia in 12 (2.1%), vertical deviations in eight (1.4%), and primary inferior oblique muscle overaction in three (0.5%). Of 67 patients with exotropia, 18 had anisometropia and 39 had amblyopia. Of the 12 patients with esotropia, four had amblyopia and none had anisometropia. Exotropia and esotropia are more common in patients with the Marfan syndrome than in the general population of the United States (P < .001 for exotropia and .05 < P < .10 for esotropia). Abnormal afferent visual inputs to cortical centers caused by ectopia lentis, craniofacial abnormalities, and mechanical and genetic factors may all contribute to the higher prevalence of strabismus in this disease. |
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Authors:
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N J Izquierdo; E I Traboulsi; C Enger; I H Maumenee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of ophthalmology Volume: 117 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-06-02 Completed Date: 1994-06-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 632-5 Citation Subset: AIM; IM |
Affiliation:
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Johns Hopkins Center for Hereditary Eye Diseases, Wilmer Ophthalmological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Amblyopia / etiology Aphakia / etiology Child Child, Preschool Female Humans Lens Subluxation / etiology Lenses, Intraocular Male Marfan Syndrome / complications* Middle Aged Prevalence Refractive Errors / etiology Strabismus / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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