Document Detail

Strabismus in Down syndrome.
MedLine Citation:
PMID:  16491722     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the distribution of refractive errors and clinical characteristics of strabismus in patients with Down syndrome. PATIENTS AND METHODS: Patients with Down syndrome attending the Izmir Association for Supporting Patients With Down Syndrome in Izmir, Turkey, were screened for strabismus and refractive errors. All patients underwent a complete eye examination including cycloplegic refraction and dilated fundus examination. Ocular alignment was evaluated using the cover test and either the Krimsky or the Hirschberg corneal reflex test depending on the cooperation of the patient. Strabismic and nonstrabismic patients were compared for refractive errors, anisometropia, and amblyopia. RESULTS: Fifty-seven patients with an average (+/- standard deviation) age of 9.30 years (+/- 6.14 years; range, 1 to 31 years) were screened. Twenty-five (44%) were female and 32 (56%) were male. Eleven patients (19%) had strabismus. Ten (18%) had esotropia and 1 (2%) had exotropia. Infantile esotropia was observed in 3 patients who had no significant refractive errors. Seven patients had acquired esotropia; they had clinically significant refractive errors and anisometropia. A higher frequency of hypermetropia was noted in patients with strabismus (P < .05). CONCLUSIONS: Esotropia and hypermetropia are common in patients with Down syndrome. Early diagnosis and treatment of strabismus and associated ocular conditions such as refractive errors and amblyopia may improve the quality of life for these patients.
Nazife Sefi Yurdakul; Seyda Ugurlu; Ahmet Maden
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of pediatric ophthalmology and strabismus     Volume:  43     ISSN:  0191-3913     ISO Abbreviation:  J Pediatr Ophthalmol Strabismus     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-02-22     Completed Date:  2006-03-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7901143     Medline TA:  J Pediatr Ophthalmol Strabismus     Country:  United States    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
Izmir Atatürk Education and Research Hospital, Department of Ophthalmology, Izmir, Turkey.
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MeSH Terms
Child, Preschool
Down Syndrome / complications*,  psychology
Eye Movements / physiology
Quality of Life
Refraction, Ocular / physiology
Refractive Errors / complications,  epidemiology,  physiopathology
Strabismus / complications*,  epidemiology,  physiopathology
Turkey / epidemiology

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