| Stool consistency and stool frequency are excellent clinical markers for adequate colon preparation after polyethylene glycol 3350 cleansing protocol: a prospective clinical study in children. | |
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MedLine Citation:
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PMID: 18950761 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Colon preparation for a colonoscopy in children is a difficult task because of the unpalatable taste and large volume of cleansing solution that needs to be consumed to ensure a clean colon. Consequently, an unprepared colon frequently occurs in routine practices, which causes early termination and a repeated procedure. OBJECTIVE: (1) To assess the effectiveness of polyethylene glycol solution (PEG 3350) in preparing the colon of children scheduled for a colonoscopy and (2) to investigate clinical markers associated with an adequate colon preparation before a colonoscopy. PATIENTS: A total of 167 children scheduled for a colonoscopy. DESIGN: In a prospective study, children scheduled for a colonoscopy were given PEG 3350 solution (1.5 g/kg per day, up to 100 g/d) over a 4-day preparation period. Each day, a simple questionnaire that documents the amount of liquid consumed, adverse effects, and the number and consistency of stool was completed by the parents. After a colonoscopy procedure, the colon preparation was assigned a number grade. The data were later assessed and were compared to determine the association between the grade of cleansing and the frequency and/or consistency of stool during preparation. RESULTS: Colon preparation was completed in 149 children, 133 of whom were adequately prepared. Inadequate preparation was found in 16 children; the procedure was terminated prematurely in 2 of these patients because of unacceptable conditions. No significant adverse effects were noted. A number of >or=5 stools/d, and liquid stool consistency in the last 2 days of preparation were associated with adequate colon preparation. CONCLUSIONS: PEG 3350 solution is safe, efficacious, and tolerable for children. Stool frequency and consistency in the last 2 days of preparation were excellent markers (positive predictive value 91%-95%), which predict an adequately clean colon before a colonoscopy in children. |
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Authors:
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Shaista Safder; Yulia Demintieva; Mary Rewalt; Yoram Elitsur |
Publication Detail:
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Type: Clinical Trial; Journal Article Date: 2008-10-23 |
Journal Detail:
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Title: Gastrointestinal endoscopy Volume: 68 ISSN: 1097-6779 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-25 Completed Date: 2009-05-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
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Languages: eng Pagination: 1131-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Gastroenterology Division, Joan C Edwards School of Medicine, Marshall University, Huntington, West Virginia 25701, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Cathartics* Child Child, Preschool Clinical Protocols Colonoscopy* Defecation* Feces* Female Humans Male Polyethylene Glycols* Prospective Studies Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Cathartics; 0/Miralax; 0/Polyethylene Glycols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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