Document Detail

Stomal recurrence after laryngectomy: interrelated risk factor study.
MedLine Citation:
PMID:  2126104     Owner:  NLM     Status:  MEDLINE    
This study was designed to identify pathogenic factors in recurrent carcinoma at the tracheal stoma. The charts of 444 patients with laryngeal cancer who were treated surgically between 1976 and 1988 revealed stomal recurrence in 15 (3.4%). Eighty percent of the patients with stomal recurrence had tumors in the subglottis. In comparison to patients with different sites involved this was significant (p less than 0.001). Other variables examined and analyzed included primary stage, previous treatment, neck pathologic status, neck treatment, age, sex, postoperative adjunctive therapy, and timing of tracheotomy. Tumor involvement of the subglottis is the single most important variable in stomal recurrence of carcinoma. Previous conservation laryngeal surgery and preoperative/emergency tracheotomy are not related to stomal recurrence of carcinoma. Mean length of survival for patients with stomal recurrence of carcinoma in our series was 8.9 months. Two patients were successfully treated with extensive surgical resection. The dismal prognosis of stomal recurrence of carcinoma suggests that management of this condition should focus on prevention. Treatment of patients with tumors of the subglottis should include attention to the paratracheal region and superior mediastinum, in conjunction with laryngectomy immediately after initial diagnosis.
J Rubin; J T Johnson; E N Myers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  103     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-03-01     Completed Date:  1991-03-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  805-12     Citation Subset:  IM    
Department of Otolaryngology, University of Pittsburgh School of Medicine, PA.
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MeSH Terms
Aged, 80 and over
Carcinoma, Squamous Cell / pathology,  surgery*,  therapy
Combined Modality Therapy
Glottis / pathology
Laryngeal Neoplasms / pathology,  surgery*,  therapy
Middle Aged
Neoplasm Recurrence, Local / etiology*,  pathology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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