Document Detail

Stochastic galvanic vestibular stimulation produces a small reduction in sway in Parkinson's disease.
MedLine Citation:
PMID:  20448339     Owner:  NLM     Status:  MEDLINE    
We investigated the effects of bicathodal stochastic galvanic vestibular stimulation (GVS) on body sway in normal subjects and in Parkinson's Disease (PD) patients. Twenty normal subjects and five PD patients were stimulated with four stimulus intensities between 0 and 0.5 mA and sway was measured in two stance conditions (on a compliant surface with either eyes open (EOCS) or closed (ECCS)). Subjects stood facing forward with their feet together on a force platform. Centre of pressure (CoP) displacement over 26 seconds was measured in the anteroposterior (AP) and mediolateral (ML) planes. GVS had no significant overall effect on sway in the normal subjects. In the patients a small (4.5%) significant decrease in sway was seen in the ECCS condition with low intensity (0.1 mA) stimulation (P=0.02). Similar changes were seen in the normal subjects. This work indicates that low intensities of stochastic GVS can reduce sway levels in PD patients for certain stance conditions.
Sudipto Pal; Sally M Rosengren; James G Colebatch
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of vestibular research : equilibrium & orientation     Volume:  19     ISSN:  1878-6464     ISO Abbreviation:  J Vestib Res     Publication Date:  2009  
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-07-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104163     Medline TA:  J Vestib Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM; S    
Prince of Wales Clinical School and Medical Research Institute, University of New South Wales, Randwick, Sydney, Australia.
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MeSH Terms
Electric Stimulation
Mastoid / physiology
Middle Aged
Parkinson Disease / physiopathology*
Postural Balance
Posture / physiology*
Stochastic Processes
Vestibule, Labyrinth / physiology*
Young Adult

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