Document Detail

Stochastic analysis of heart rate variability and its relation to echocardiography parameters in hypertrophic cardiomyopathy patients.
MedLine Citation:
PMID:  21071828     Owner:  NLM     Status:  In-Process    
The heart rate variability of 10 healthy males (age 26 - 4/+ 3 y) and 49 patients with hypertrophic cardiomyopathy (HCM) (25 males, 24 females, age 29.5 - 11.5/+ 10.5 y) was studied. We applied Kramers-Moyal expansion to extract the drift and diffusion terms of the Langevin equation for the RR interval time series. These terms may be used for a stochastic reconstruction of the time series and for description of the properties of heart rate variability. New parameters characterizing the diffusion term are proposed: the coefficients of the linear fit to the left (LCF) and right (RCF) branch of the dependence of the diffusion term on the rescaled heart rate. Relations of the new parameters to classical echocardiography parameters were studied. Using the relation between the difference LCF-RCF and the left ventricular systolic diameter, the HCM patients studied were divided into three groups. In addition, comparison of the properties of the heart rate variability in the HCM group with that obtained for the healthy young men showed that the parameter LCF-RCF may be treated as a measure of the effect of HCM on heart rate variability and may have diagnostic value.
M Petelczyc; J J Zebrowski; R Baranowski; L Chojnowska
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-11-12
Journal Detail:
Title:  Physiological measurement     Volume:  31     ISSN:  1361-6579     ISO Abbreviation:  Physiol Meas     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  England    
Other Details:
Languages:  eng     Pagination:  1635-49     Citation Subset:  IM    
Faculty of Physics, Warsaw University of Technology, Koszykowa 75, Warsaw, Poland.
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