Document Detail


Stimulus-induced seizure in sick neonates--novel observations with potential clinical implications.
MedLine Citation:
PMID:  19732131     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stimulus-induced seizure is a well-described entity in children and adults and is often associated with severe epilepsy and neurologic impairment. The occurrence and clinical expression of stimulus-induced seizure in three sick neonates is described. The cohort comprised 26 neonates undergoing continuous video-electroencephalography (vEEG) monitoring between July and December 2007. Three cases (11.5%) of stimulus-induced seizure were identified. The underlying injury included stroke (n = 2) and intraventricular hemorrhage (n = 1). Seizures were induced by physical stimuli such as stroking the forehead, movements, (i.e., starting to feed), and one during endotracheal suctioning. Stimulus-evoked electrographic patterns have been reported in neonates with brain injury; however, these events appear to be more common than previously thought, especially with the abundance of subclinical seizures observed in these patients. These observations stress the usefulness of vEEG monitoring and importance of care to avoid unnecessary stimuli in at-risk neonates.
Authors:
Toshiki Takenouchi; Vivien L Yap; Murray Engel; Jeffrey M Perlman
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-03
Journal Detail:
Title:  Epilepsia     Volume:  51     ISSN:  1528-1167     ISO Abbreviation:  Epilepsia     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-24     Completed Date:  2010-04-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  308-11     Citation Subset:  IM    
Affiliation:
Division of Pediatric Neurology, Department of Pediatrics, NewYork-Presbyterian Hospital, Weill Cornell Medical College, New York, New York, USA. tot9005@nyp.org
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MeSH Terms
Descriptor/Qualifier:
Brain / physiopathology*
Cerebrovascular Disorders / diagnosis,  physiopathology
Electroencephalography / methods,  statistics & numerical data*
Epilepsies, Partial / diagnosis,  etiology
Epilepsy, Reflex / diagnosis,  epidemiology,  etiology,  physiopathology*
Female
Humans
Image Interpretation, Computer-Assisted / methods
Infant, Newborn
Infarction, Middle Cerebral Artery / diagnosis,  physiopathology
Male
Monitoring, Physiologic / methods
Physical Stimulation / methods
Stroke / diagnosis,  physiopathology
Videotape Recording / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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