| Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea. II: Frequency and interpulse interval. | |
| | |
MedLine Citation:
|
PMID: 8408969 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Psychophysical detection thresholds for electrical stimulation of the cochlea were measured in nonhuman primates (macaques) as part of a series of experiments exploring the stimulus features affecting detection. The monkeys were trained psychophysically using operant conditioning. One ear was treated with neomycin to destroy hair cells, and implanted with electrodes in the scala tympani and/or the cochlear wall. In experiment 1, detection thresholds were measured for trains of fixed-duration pulses and for sinusoids. For long-duration pulses (1 to 2 ms/phase), thresholds decreased as a function of frequency (pulse rate), reaching a minimum at a frequency between 125 and 210 pps, then increased as frequency was further increased. For shorter duration pulses, thresholds usually decreased monotonically as a function of frequency but sometimes showed a slight increase as a function of frequency near the highest frequencies tested. Typically slopes of the threshold versus frequency functions for fixed-duration pulses were equal to or less than slopes of threshold versus frequency functions for sinusoidal signals, where frequency and phase duration covaried. Additional observations on two of the cases were made in experiments 2 and 3. In experiment 2, thresholds for pairs of pulses were measured as a function of interpulse interval. Thresholds decreased as a function of interpulse interval up to intervals of 2 to 4 ms and then increased slightly. In experiment 3, thresholds were measured as a function of stimulus duration at two frequencies.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
B E Pfingst; D J Morris |
Related Documents
:
|
19291749 - Pulsing influences photoradiation outcomes in cell culture. 22468889 - Studying light propagation in self-assembled hybrid photonic-plasmonic crystals by four... 7823619 - Automating the generation and collection of rate-frequency functions in a curve-shift b... 12417979 - Influence of the pulse duration of an er:yag laser system on the ablation threshold of ... 17347019 - Effect of exposure parameters on cavitation induced by low-level dual-frequency ultraso... 12765409 - Pulse register phonation in diana monkey alarm calls. 21478509 - The relationship between different adaptational changes and injury in the dominant shou... 3832619 - Two types of trichromatic squirrel monkey share a pigment in the red-green spectral reg... 8084729 - Discrimination of auditory temporal patterns. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: The Journal of the Acoustical Society of America Volume: 94 ISSN: 0001-4966 ISO Abbreviation: J. Acoust. Soc. Am. Publication Date: 1993 Sep |
Date Detail:
|
Created Date: 1993-11-17 Completed Date: 1993-11-17 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7503051 Medline TA: J Acoust Soc Am Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1287-94 Citation Subset: IM |
Affiliation:
|
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical Center, Ann Arbor 48109-0506. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Auditory Pathways / physiology Auditory Perception / physiology* Auditory Threshold* / physiology Cochlea / physiology* Conditioning, Operant Electric Stimulation* Electrodes, Implanted Hair Cells, Auditory / drug effects Macaca mulatta Macaca radiata Male Neomycin / adverse effects, pharmacology Psychophysics Reinforcement (Psychology) Vestibulocochlear Nerve / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
NIDCD DC00274/DC/NIDCD NIH HHS |
| Chemical | |
Reg. No./Substance:
|
1404-04-2/Neomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Loudness adaptation at high frequencies.
Next Document: Contributions of comodulation masking release and temporal resolution to the speech-reception thresh...