Document Detail


Stimulatory effect of an LHRH-agonist on testicular blood flow in hypophysectomized rats.
MedLine Citation:
PMID:  6384066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of an LHRH-agonist (A) on testicular blood flow and plasma testosterone levels was studied in adult hypophysectomized rats. Subcutaneous injection of 1 microgram LHRH-agonist 2 or 4 h prior to experiment induced an increase in testicular blood flow. (Controls: 21.1 +/- 2.8 ml/100 g X min; LHRH-A + 2 h: 28.9 +/- 3.3 ml/100 g X min; LHRH-A + 4 h: 32.4 +/- 4.1 ml/100 g X min P less than 0.05; all mean +/- SEM). There was also a significant increase in plasma testosterone levels at 2 h (P less than 0.01) and 4 h (P less than 0.01) after treatment with the LHRH-agonist, with a peak at 2 h.
Authors:
J E Damber; A Bergh; L Daehlin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of andrology     Volume:  7     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-11-02     Completed Date:  1984-11-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  236-43     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Epididymis / blood supply
Gonadotropin-Releasing Hormone / analogs & derivatives*,  pharmacology
Hypophysectomy*
Male
Rats
Regional Blood Flow / drug effects
Testis / blood supply*
Testosterone / blood
Chemical
Reg. No./Substance:
33515-09-2/Gonadotropin-Releasing Hormone; 52435-06-0/surfagon; 58-22-0/Testosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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