Document Detail

Stimulation of prostaglandin E production in superfused human amnion by human amniotic fluid.
MedLine Citation:
PMID:  3583087     Owner:  NLM     Status:  MEDLINE    
We studied the effects of human amniotic fluid (HAF) on the production of prostaglandin E (PGE) by amnion tissues using a technique of fresh-tissue superfusion. The production of PGE was linear with time for 4.5 h by amnion tissues superfused either with medium alone or with medium plus HAF (30% v/v). Tissues superfused with medium plus HAF produced significantly more PGE than tissues superfused with medium alone. Additionally, amnion tissue obtained at cesarean section, prior to labor, displayed a greater responsiveness to HAF than did amnion obtained after spontaneous labor.
D M Strickland; M D Mitchell
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  23     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1987  
Date Detail:
Created Date:  1987-06-26     Completed Date:  1987-06-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  IM    
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MeSH Terms
Amnion / metabolism*
Amniotic Fluid / physiology*
Cesarean Section
Infant, Newborn
Prostaglandins E / biosynthesis*
Grant Support
Reg. No./Substance:
0/Prostaglandins E

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