Document Detail


Stimulated single-fiber EMG of the frontalis and orbicularis oculi muscles in ocular myasthenia gravis.
MedLine Citation:
PMID:  14506723     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed single-fiber electromyography by axonal stimulation (stimulated SFEMG) of the frontalis and orbicularis oculi muscles of 20 patients with ocular myasthenia gravis (OM) and 46 controls. In controls, mean consecutive differences (MCD) ranged from 5 to 55 micros (average, 14.7 +/- 2.8 micros) in the frontalis and from 4 to 56 micros (average, 12.56 +/- 2.19 micros) in orbicularis oculi. The mean MCD of individual muscle potentials (MPs) was 14.6 +/- 6.8 micros in frontalis and 12.68 +/- 6.10 micros in orbicularis oculi. In the OM patients, the mean MCD was 43.85 +/- 25.18 micros in the frontalis and 69.85 +/- 29.55 micros in orbicularis oculi (P < 0.0001), and the number of MPs with altered MCD was 7.15 +/- 4.66 (range, 1-18) and 12.65 +/- 4.90 (range, 6-21), respectively (P < 0.0001). We conclude that stimulated SFEMG of the orbicularis oculi muscle is more sensitive for the diagnosis of OM than of the frontalis muscle.
Authors:
J Valls-Canals; M Povedano; J Montero; J Pradas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  28     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-24     Completed Date:  2003-10-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  United States    
Other Details:
Languages:  eng     Pagination:  501-3     Citation Subset:  IM    
Affiliation:
Unitat de Neuromuscular i Electromiografia, Institut Universitari Dexeus, Calatrava 83, 6 planta, 08017 Barcelona, Spain. unmemg@comb.es
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Case-Control Studies
Electromyography
Facial Muscles / physiopathology*
Female
Frontal Bone
Humans
Male
Middle Aged
Muscle Fibers, Skeletal
Myasthenia Gravis / physiopathology*
Oculomotor Muscles / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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