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Stillbirth and fetal growth restriction.
MedLine Citation:
PMID:  20661051     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The association between stillbirth and fetal growth restriction is strong and supported by a large body of evidence and clinically employed for the stillbirth prediction. However, although assessment of fetal growth is a basis of clinical practice, it is not trivial. Essentially, fetal growth is a result of the genetic growth potential of the fetus and placental function. The growth potential is the driving force of fetal growth, whereas the placenta as the sole source of nutrients and oxygen might become the rate limiting element of fetal growth if its function is impaired. Thus, placental dysfunction may prevent the fetus from reaching its full genetically determined growth potential. In this sense fetal growth and its aberration provides an insight into placental function. Fetal growth is a proxy for the test of the effectiveness of placenta, whose function is otherwise obscured during pregnancy.
Authors:
Radek Bukowski
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  53     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  673-80     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA. rkbukows@utmb.edu
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