| Stilbenes and Tyrosol as Target Compounds in the Assessment of Antioxidant and Hypolipidemic Activity of Vitis vinifera Red Wines from Southern Brazil. | |
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MedLine Citation:
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PMID: 21718033 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The contents of stilbene monomers, cis-resveratrol, trans-resveratrol, cis-piceid, trans-piceid, and tyrosol, were quantified in Vitis vinifera red wines, cvs. Cabernet Franc, Merlot, Sangiovese, and Syrah, 2006 and 2007 vintages, from the São Joaquim region, a new grape-growing region at southern Brazil. Moreover, the effect of chronic consumption of these wines on the antioxidant and hypolipidemic activities was monitored in C57BL6 LDL receptor knockout mice and treated with a hypercholesterolemic diet. Red wines from this region had substantial levels of resveratrols (the predominant forms were glycoside and trans) and tyrosol. Biomonitoring of antioxidant and hypolipidemic activities in vivo revealed that consumption of these wines increased the antioxidant capacity and reduced the hypercholesterolemia and hypertriglyceridemia promoted by the hypercholesterolemic diet. Significant correlations were found between the increase of antioxidant capacity markers, the decrease of lipid levels promoted by wine consumption, and the contents of stilbenes and tyrosol, supporting the important biological activity of these compounds. |
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Authors:
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Eliana Fortes Gris; Fulvio Mattivi; Eduardo Antonio Ferreira; Urska Vrhovsek; Danilo Wilhelm Filho; Rozangela Curi Pedrosa; Marilde T Bordignon-Luiz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-30 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-7-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Departamento de Ciência e Tecnologia de Alimentos, CAL, ‡Departamento de Bioquímica, BQA, and ¥Departamento de Ecologia e Zoologia, Universidade Federal de Santa Catarina , Rod. Admar Gonzaga, 1346, Itacorubi, CEP 88034-001, Florianópolis, SC, Brazil. |
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