| Stiff-persons' syndrome associated with thymoma and subsequent myasthenia gravis. | |
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MedLine Citation:
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PMID: 9121508 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the first case of stiff-persons' (-man) syndrome in the setting of a histologically proven thymoma. Muscular hyperactivity was abolished under general anesthesia and the symptoms of stiffness resolved after thymectomy and three courses of intravenous immunoglobulins. After thymectomy, the patient developed ocular myasthenia gravis which later resolved spontaneously. We suggest that thymoma be sought for in cases with neuromuscular hyperactivity syndromes. Myasthenia gravis may develop subsequently in these cases. |
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Authors:
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A P Nicholas; A Chatterjee; M M Arnold; G C Claussen; G L Zorn; S J Oh |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Muscle & nerve Volume: 20 ISSN: 0148-639X ISO Abbreviation: Muscle Nerve Publication Date: 1997 Apr |
Date Detail:
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Created Date: 1997-04-24 Completed Date: 1997-04-24 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7803146 Medline TA: Muscle Nerve Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 493-8 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Alabama at Birmingham, 35294-0007, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Electromyography Humans Male Middle Aged Muscle, Skeletal / physiopathology Myasthenia Gravis / etiology*, physiopathology Postoperative Complications Stiff-Person Syndrome / etiology*, physiopathology Thymectomy* Thymoma / complications*, pathology, surgery Thymus Neoplasms / complications*, pathology, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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