| Stiff-man syndrome associated with antecedent myasthenia gravis and organ-specific autoimmunopathy. | |
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MedLine Citation:
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PMID: 9187573 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a case of stiff-man syndrome accompanied by diabetes mellitus, Hashimoto's thyroiditis and the antecedent myasthenia gravis. The diagnosis of stiff-man syndrome was made based on not only clinical findings and the characteristic electromyographic pattern but also the presence of antibodies to glutamic acid decarboxylase in the serum and cerebrospinal fluid. Stiff-man syndrome is known to be associated with organ-specific autoimmunopathy including insulin-dependent diabetes mellitus. The present case is the first one that stiff-man syndrome was preceded by myasthenia gravis of organ-specific autoimmunopathy. Stiff-man syndrome in the present case probably represents the one of fully expressed manifestations from the broad spectrum of organ-specific autoimmunopathy caused by the loss of self-tolerance. |
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Authors:
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Y Aso; A Sato; M Narimatsu; Y Takiguchi; Y Yamaguchi; T Inukai; Y Takemura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 36 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 1997 Apr |
Date Detail:
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Created Date: 1997-08-01 Completed Date: 1997-08-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 308-11 Citation Subset: IM |
Affiliation:
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Department of Medicine, Koshigaya Hospital, Dokkyo University School of Medicine, Saitama. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autoimmune Diseases / complications* Diabetes Mellitus, Type 1 / complications* Female Humans Myasthenia Gravis / complications* Stiff-Person Syndrome* / diagnosis, etiology, immunology Thyroiditis, Autoimmune / complications* |
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