| Stiff-leg syndrome: a focal form of stiff-man syndrome. | |
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MedLine Citation:
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PMID: 9506561 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report on 2 patients who presented stiffness and spasms similar to those of stiff-man syndrome (SMS) that were limited to one leg for up to 11 years. Patients had serum glutamic acid decarboxylase (GAD) autoantibodies in high titer, clinical evidence of organ-specific autoimmunity, and electromyographic pattern of continuous motor unit activity with abnormally enhanced exteroceptive reflexes. The clinical and immunological profile suggests that this disorder may be a focal form of SMS. |
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Authors:
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A Saiz; F Graus; F Valldeoriola; J Valls-Solé; E Tolosa |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of neurology Volume: 43 ISSN: 0364-5134 ISO Abbreviation: Ann. Neurol. Publication Date: 1998 Mar |
Date Detail:
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Created Date: 1998-04-10 Completed Date: 1998-04-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7707449 Medline TA: Ann Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 400-3 Citation Subset: IM |
Affiliation:
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Service of Neurology, Department of Medicine, Hospital Clínic i Provincial, University of Barcelona, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoantibodies
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analysis Electromyography Female Glutamate Decarboxylase / immunology Humans Leg / physiopathology* Middle Aged Muscle, Skeletal / physiopathology Reflex / physiology Stiff-Person Syndrome / classification, immunology, physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; EC 4.1.1.15/Glutamate Decarboxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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