Document Detail


Sticking together: building a biofilm the Bacillus subtilis way.
MedLine Citation:
PMID:  23353768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biofilms are ubiquitous communities of tightly associated bacteria encased in an extracellular matrix. Bacillus subtilis has long served as a robust model organism to examine the molecular mechanisms of biofilm formation, and a number of studies have revealed that this process is regulated by several integrated pathways. In this Review, we focus on the molecular mechanisms that control B. subtilis biofilm assembly, and then briefly summarize the current state of knowledge regarding biofilm disassembly. We also discuss recent progress that has expanded our understanding of B. subtilis biofilm formation on plant roots, which are a natural habitat for this soil bacterium.
Authors:
Hera Vlamakis; Yunrong Chai; Pascale Beauregard; Richard Losick; Roberto Kolter
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2013-01-28
Journal Detail:
Title:  Nature reviews. Microbiology     Volume:  11     ISSN:  1740-1534     ISO Abbreviation:  Nat. Rev. Microbiol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-15     Completed Date:  2013-04-12     Revised Date:  2014-03-06    
Medline Journal Info:
Nlm Unique ID:  101190261     Medline TA:  Nat Rev Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  157-68     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Bacillus subtilis / physiology*
Bacterial Adhesion*
Biofilms / growth & development*
Gene Expression Regulation, Bacterial
Models, Biological
Plant Roots / microbiology
Grant Support
ID/Acronym/Agency:
GM18546/GM/NIGMS NIH HHS; GM58213/GM/NIGMS NIH HHS; R01 GM018568/GM/NIGMS NIH HHS; R01 GM058213/GM/NIGMS NIH HHS
Comments/Corrections

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