Document Detail


Stevens-Johnson syndrome limited to multiple sites of radiation therapy in a patient receiving phenobarbital.
MedLine Citation:
PMID:  10071329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to a medication. There have been 21 reported cases of atypical erythema multiforme, toxic epidermal necrolysis, and SJS arising in patients receiving radiation therapy in addition to phenytoin, phenobarbital, or carbamazepine. We report the second case of SJS resulting from concomitant phenobarbital and radiation therapy, in which the eruption was limited to the sites of radiation, which were multiple.
Authors:
K O Duncan; R E Tigelaar; J L Bolognia
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  40     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-01     Completed Date:  1999-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  493-6     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA.
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MeSH Terms
Descriptor/Qualifier:
Biopsy
Combined Modality Therapy
Humans
Male
Middle Aged
Phenobarbital / adverse effects*
Radiotherapy / adverse effects*
Stevens-Johnson Syndrome / etiology*,  pathology
Chemical
Reg. No./Substance:
50-06-6/Phenobarbital

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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