| Stevens-Johnson syndrome induced by acetazolamide. | |
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MedLine Citation:
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PMID: 21342230 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Acetazolamide is a sulfonamide derivative and carbonic anhydrase inhibitor used to lower intraocular pressure in glaucomatous patients. Stevens-Johnson syndrome (SJS) toxic epidermal necrolysis (TEN) associated with acetazolamide treatment has been diagnosed in Japanese, Japanese-American and Indian patients. Herein, we report the second Korean case of SJS-TEN associated with acetazolamide treatment. The result of human leukocyte antigen (HLA) typing of our patient was positive for HLA-B59. According to recent research, HLA-B59 has been detected in SJS caused by metazolamide, which is analogous to acetazolamide. This suggests a possible relationship between genetic background and SJS-TEN-associated acetazolamide treatment. Theretofore, acetazolamide should be prescribed to Korean patients with the same discreet caution. |
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Authors:
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Young Her; Min S Kil; Ju H Park; Chul W Kim; Sang S Kim |
Publication Detail:
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Type: Journal Article Date: 2010-12-13 |
Journal Detail:
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Title: The Journal of dermatology Volume: 38 ISSN: 1346-8138 ISO Abbreviation: J. Dermatol. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 272-5 Citation Subset: IM |
Copyright Information:
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© 2010 Japanese Dermatological Association. |
Affiliation:
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Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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