Document Detail

Stevens-Johnson syndrome in children.
MedLine Citation:
PMID:  7145729     Owner:  NLM     Status:  MEDLINE    
During a 22-year period 51 cases of Stevens-Johnson syndrome (SJS) occurred in infants and children who ranged in age from 3 months to 14 years. Fifty-six percent of patients had an antecedent upper respiratory tract infection or non-specific viral infection, and 67% had received a prescription medication in the 3 weeks before onset of SJS. Nineteen patients (37%) were treated with adrenocorticosteroid medication during their hospitalization. Age, sex, duration of illness, body temperature on admission and history of antecedent medication were similar for the steroid- and non-steroid-treated patients. Rates of infection and overall complications were significantly greater in steroid-treated patients than in those treated symptomatically. These observations suggest that steroid drugs should not be used for treatment of SJS in infants and children.
C M Ginsburg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric infectious disease     Volume:  1     ISSN:  0277-9730     ISO Abbreviation:  Pediatr Infect Dis     Publication Date:    1982 May-Jun
Date Detail:
Created Date:  1983-01-19     Completed Date:  1983-01-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8209468     Medline TA:  Pediatr Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  155-8     Citation Subset:  IM    
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Anti-Bacterial Agents / therapeutic use
Anticonvulsants / therapeutic use
Bacterial Infections / etiology
Child, Preschool
Fluid Therapy
Stevens-Johnson Syndrome / complications,  diagnosis,  therapy*
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents; 0/Anticonvulsants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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