Document Detail


Stevens-Johnson syndrome in a boy with nephrotic syndrome during prednisolone therapy.
MedLine Citation:
PMID:  12836099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stevens-Johnson syndrome (SJS) is a mucocutaneous disease that can be lethal. It can occur in association with altered immunological conditions and the administration of various drugs, including corticosteroids. We report a case of SJS in a 14-year-old male with nephrotic syndrome, who was treated with oral prednisolone for 6 weeks. He presented symptoms of fever, skin lesions consisting of multiple vesiculopapular rashes, pruritic maculae and bullae, and mucosal involvement of the eyes, lips, oral cavity, and anorectal junction. His condition improved without complications following the discontinuation of oral prednisolone and replacement with intravenous methylprednisolone. Following the improvement of the symptoms of SJS, he received alternate-day oral prednisolone without any cutaneous eruption.
Authors:
Dae Sun Jo; Jun-Won Yang; Pyoung Han Hwang; Dae-Yeol Lee
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2003-06-26
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  18     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-20     Completed Date:  2004-04-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  959-61     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Chonbuk National University Medical School, 634-18 Keumam-dong, Jeonju 561-712, Korea.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adolescent
Glucocorticoids / administration & dosage,  adverse effects*
Humans
Injections, Intravenous
Male
Methylprednisolone / administration & dosage
Nephrotic Syndrome / complications*,  drug therapy*
Prednisolone / administration & dosage,  adverse effects*
Stevens-Johnson Syndrome / complications*,  etiology
Chemical
Reg. No./Substance:
0/Glucocorticoids; 50-24-8/Prednisolone; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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