Document Detail


Stevens-Johnson syndrome: a case report.
MedLine Citation:
PMID:  20587964     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal anti-inflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one such potentially lethal adverse drug reaction. Most reported cases of analgesic-induced Stevens-Johnson syndrome were due to oxicams or propionic acid derivatives. There are very few detailed reports of Stevens-Johnson syndrome due to use of diclofenac. We report here a case of Stevens-Johnson syndrome which occurred due to use of diclofenac sodium. The clinical features of this condition and multidisciplinary management of the patient are described in brief.
Authors:
Shishir R Shetty; Laxmikanth Chatra; Prashanth Shenai; Prasanna K Rao
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of oral science     Volume:  52     ISSN:  1880-4926     ISO Abbreviation:  J Oral Sci     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-30     Completed Date:  2010-09-30     Revised Date:  2011-11-03    
Medline Journal Info:
Nlm Unique ID:  9808942     Medline TA:  J Oral Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  343-6     Citation Subset:  D; IM    
Affiliation:
Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India. drshishirshettyomr@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
Conjunctival Diseases / chemically induced
Dental Caries / therapy
Diclofenac / adverse effects*
Female
Follow-Up Studies
Humans
Leg Ulcer / chemically induced
Middle Aged
Oral Ulcer / chemically induced
Pain, Postoperative / drug therapy
Skin Ulcer / chemically induced
Stevens-Johnson Syndrome / chemically induced*
Tooth Extraction
Ulcer / chemically induced
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 15307-86-5/Diclofenac

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