Document Detail

Steroids for LBP - from rationale to inconvenient truth.
MedLine Citation:
PMID:  22495738     Owner:  NLM     Status:  In-Data-Review    
Low back pain (LBP) and sciatica are highly prevalent and their treatment remains a clinical challenge. Systemic or local administration of corticosteroids is frequently prescribed for this indication, partly because its pathogenesis is believed to be a mix between mechanical and inflammatory phenomenon, and because corticosteroids do have some analgesic properties. Although there is some biological and animal data in favour of the use of corticosteroids in LBP and sciatica, clinical evidence remains scarce. Local epidural injection can have some short term benefit. However, we found no support for any type for systemic administration of corticosteroids, a practice that should definitively be banned.
F Balagué; V Piguet; J Dudler
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Publication Detail:
Type:  Journal Article     Date:  2012-04-11
Journal Detail:
Title:  Swiss medical weekly     Volume:  142     ISSN:  1424-3997     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2012  
Date Detail:
Created Date:  2012-04-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  0     Citation Subset:  IM    
Clinique de rhumatologie et Service de médecine physique et rééducation, HFR Fribourg - Hôpital Cantonal, Switzerland;
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