Document Detail

Steroid-responsive polyneuropathy with subacute onset in childhood.
MedLine Citation:
PMID:  7411298     Owner:  NLM     Status:  MEDLINE    
Five pediatric patients with subacute onset polyneuropathy are presented, with electrophysiologic and pathologic data. All patients improved, the majority to resolution, with administration of prednisone. Distinguishing factors included (1) subacute onset polyneuropathy progressing gradually over weeks to months, (2) primarily motor neuropathy with little cranial nerve involvement, (3) elevated CSF protein concentration, (4) markedly delayed nerve conduction velocities, and (5) tendency toward relapse and recurrence. Although this disorder may share characteristics with the Guillain-Barré syndrome, its steroid responsiveness sets it apart clinically from the acute form of the disease. Because of the steroid responsiveness, it is important to recognize this entity.
R V Colan; O C Snead; S J Oh; J W Benton
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  97     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1980-11-25     Completed Date:  1980-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  374-7     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Diagnosis, Differential
Polyneuropathies / diagnosis*,  drug therapy
Polyradiculoneuropathy / diagnosis
Prednisone / therapeutic use
Reg. No./Substance:

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