Document Detail


Steroid-responsive nephrotic syndrome in a child with juvenile idiopathic arthritis.
MedLine Citation:
PMID:  18038156     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Renal disease is rare in children with juvenile idiopathic arthritis, although a number of associated nephropathies have been described, including mesangial glomerulonephritis. We report the presence of mesangial glomerulonephritis, revealed by a nephrotic syndrome, in a paediatric patient with juvenile idiopathic arthritis. Short-term steroid treatment induced a rapid remission of the nephrotic syndrome, but the presence of anti-nuclear antibodies, 1:320 in a homogeneous pattern, irregular deposits of C1q in a renal biopsy, and a mother with episodes of cutaneous lupus suggested an uncertain renal evolution for this infant.
Authors:
Flavio Bandin; Marion Merhenberger; Anne Modesto; Karine Brochard; Stéphane Decramer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-11-24
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  23     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-03     Completed Date:  2008-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  651-4     Citation Subset:  IM    
Affiliation:
Department of Paediatric Nephrology, Children's Hospital, Centre de Référence du Sud-Ouest des Maladies Rénales Rares, Toulouse, France. bandin.f@chu-toulouse.fr
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Arthritis, Juvenile Rheumatoid / complications*,  drug therapy*,  pathology
Drug Therapy, Combination
Female
Glomerular Mesangium / metabolism,  pathology
Glucocorticoids / therapeutic use*
Humans
Infant
Kidney / metabolism,  pathology
Microscopy, Fluorescence
Nephrotic Syndrome / complications*,  drug therapy*,  pathology
Prednisone / therapeutic use*
Remission Induction
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Glucocorticoids; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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