Document Detail


Steroid-responsive encephalopathy and autoimmune thyroiditis in a young boy.
MedLine Citation:
PMID:  21763957     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Steroid-responsive encephalopathy with autoimmune thyroiditis is a relatively uncommon entity in the pediatric population. Although the pathogenesis of steroid-responsive encephalopathy with autoimmune thyroiditis is uncertain, an autoimmune mechanism is suspected to be the most likely cause. Seizures of unknown etiology are a common presenting sign in the pediatric intensive care unit, and steroid-responsive encephalopathy with autoimmune thyroiditis should be considered as a possible cause of recurrent seizures. The outcome of steroid-responsive encephalopathy with autoimmune thyroiditis is variable in children, and is partly dependent on early diagnosis and the administration of intravenous steroids. Only 31 pediatric cases of steroid-responsive encephalopathy with autoimmune thyroiditis were described in the English-language literature since 1966. Very few were reported in the United States or among males. We describe a 13-year-old boy presenting with a new onset of seizures as a manifestation of steroid-responsive encephalopathy with autoimmune thyroiditis. This report presents, to the best of our knowledge, the youngest male with steroid-responsive encephalopathy with autoimmune thyroiditis, and the only reported child with other autoimmune manifestations in addition to encephalopathy.
Authors:
Sanket D Shah; Hema Murali
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  45     ISSN:  1873-5150     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  132-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Pediatrics, Marshfield Clinic, Marshfield, Wisconsin.
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