| Steroid-resistant nephrotic syndrome associated with Kimura's disease. | |
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MedLine Citation:
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PMID: 12169873 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Kimura's disease is a chronic inflammatory disease characterized by tumor-like lesions in the soft tissue and lymph nodes of head and neck area or parotid gland. It has a high frequency of an association with nephrotic syndrome. Reported cases of nephrotic syndrome and Kimura's disease were mostly from adult patients with only 5 children mentioned. This study reports the case of a 15-year-old-boy who manifested with steroid-resistant nephrotic syndrome for 4 years. Pathological examination of the kidney revealed mild mesangial proliferation. Subsequently, he developed a soft-tissue mass in the parotid gland area. Histopathological investigation of the mass revealed eosinophilic infiltration together with plasma cells and mast cells which is a main characteristic of Kimura's disease. The patient, however, continued to have nephrotic-range proteinuria after removing the subcutaneous mass. |
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Authors:
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Wattana Chartapisak; Sauwalak Opastirakul |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of nephrology Volume: 22 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 2002 Jul-Aug |
Date Detail:
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Created Date: 2002-08-09 Completed Date: 2002-10-04 Revised Date: 2007-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 381-4 Citation Subset: IM |
Copyright Information:
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Copyright 2002 S. Karger AG, Basel |
Affiliation:
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Renal Unit, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Thailand. wchartap@med.cmu.ac.th |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Angiolymphoid Hyperplasia with Eosinophilia / complications* Anti-Inflammatory Agents / therapeutic use* Cyclophosphamide / therapeutic use Dermatologic Agents / therapeutic use Drug Resistance* Humans Immunosuppressive Agents / therapeutic use Kidney / pathology Male Nephrotic Syndrome / complications*, drug therapy*, pathology Prednisolone / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Dermatologic Agents; 0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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