Document Detail

Steroid-induced psychosis in an adolescent: treatment and prophylaxis with risperidone.
MedLine Citation:
PMID:  17172069     Owner:  NLM     Status:  MEDLINE    
Steroid-induced psychotic disorder is one of the serious adverse effects of corticosteroid therapy and is characterized by hallucinations and delusions. While the mechanism is unclear, treatment of steroid psychosis involves dosage reduction or discontinuation of prednisone. In cases where this cannot be done, typical treatment involves an antipsychotic medication. Although it is a well-known complication in adulthood, literature about steroid-induced psychotic disorder in children and adolescents is lacking. Here we report a 12-year-old case of steroid-induced psychotic disorder who was treated with an atypical antipsychotic, risperidone, and in whom the antipsychotic therapy was maintained because of continuation of her corticosteroid treatment for nephrotic syndrome. Pediatricians should be aware of this rare problem when prescribing corticosteroids in this age group. To our knowledge, this is the first reported case of steroid-induced psychosis successfully treated with risperidone in an adolescent with nephrotic syndrome.
Sabri Hergüner; Ilmay Bilge; Alev Yavuz Yilmaz; Dilara Umran Tüzün
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  48     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2006 Jul-Sep
Date Detail:
Created Date:  2006-12-18     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  244-7     Citation Subset:  IM    
Department of Child and Adolescent Psychiatry, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
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MeSH Terms
Antipsychotic Agents / therapeutic use*
Glucocorticoids / adverse effects*
Prednisone / adverse effects*
Psychoses, Substance-Induced / drug therapy*
Risperidone / therapeutic use*
Reg. No./Substance:
0/Antipsychotic Agents; 0/Glucocorticoids; 106266-06-2/Risperidone; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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