Document Detail


Steroid atrophy--a histological appraisal.
MedLine Citation:
PMID:  133833     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This histological changes induced by 1 month's applications of various corticorteroids to normal forearm skin were studied. Marked epidermal atrophy was present at 1 month with the more potent steroids, but the dermal changes were minimal or absent. The methods outlined in this study could serve as a useful model for assessing the unwanted atrophogenic action of potent corticosteroid preparations.
Authors:
E W Jones
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Dermatologica     Volume:  152 Suppl 1     ISSN:  0011-9075     ISO Abbreviation:  Dermatologica     Publication Date:  1976  
Date Detail:
Created Date:  1976-11-01     Completed Date:  1976-11-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0211607     Medline TA:  Dermatologica     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  107-15     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Atrophy
Betamethasone / analogs & derivatives*
Betamethasone 17-Valerate / pharmacology*
Clinical Trials as Topic
Drug Eruptions / etiology
Humans
Hydrocortisone / analogs & derivatives*,  pharmacology*
Male
Middle Aged
Ointments
Skin / drug effects,  pathology*
Skinfold Thickness
Time Factors
Chemical
Reg. No./Substance:
0/Ointments; 2152-44-5/Betamethasone 17-Valerate; 378-44-9/Betamethasone; 50-23-7/Hydrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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