Document Detail


Stereotactic radiation therapy for optic nerve sheath meningioma; an experience at Ramathibodi Hospital.
MedLine Citation:
PMID:  17128842     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate results of stereotactic radiotherapy for the treatment of optic nerve sheath meningioma (OM) at Ramathibodi Hospital. MATERIAL AND METHOD: Twelve patients with primary OM were treated with stereotactic radiation between 1998 and 2005. Five patients underwent surgery and had no light perception before radiation. All patients except one were treated with fractionated stereotactic radiotherapy (FSRT). Mean average dose of FSRT was 55. 7 Gy; 180 cGy/fraction. One patient was treated with 15-Gy stereotactic radiosurgery. RESULTS: With a median follow-up of 34 months, there was no visual improvement in the five patients who were completely blind before radiation. Visual acuity improved in four patients and remained stable in two patients. Four of six patients had improved visual field, and five of six decreased in proptosis. Follow-up images were available in six patients, showing minimal tumor regression in five and stable in one. No serious acute side effect was observed. Vision became worse in one patient, who developed vitreous hemorrhage two years after FSRT. CONCLUSION: Stereotactic radiotherapy is an effective treatment for primary OM. It provides tumor control and visual preservation with low risk of complications. However more patients and further follow-up are needed for long-term outcomes.
Authors:
Chomporn Sitathanee; Mantana Dhanachai; Anuchit Poonyathalang; Lojana Tuntiyatorn; Veerasak Theerapancharoen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  89     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-11-28     Completed Date:  2007-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  1665-9     Citation Subset:  IM    
Affiliation:
Division of Radiation Oncology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. racsi@mahidol.ac.th
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Hospitals
Humans
Male
Meningeal Neoplasms / pathology,  surgery*
Meningioma / pathology,  surgery*
Middle Aged
Optic Nerve Neoplasms / pathology,  surgery*
Radiosurgery*
Thailand
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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