| Stereoselective intramolecular cyclization in irradiated nucleic acids: R- and S-8,5'-cycloadenosine in polyadenylic acid. | |
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MedLine Citation:
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PMID: 3947353 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The yields of R- and S-8,5'-cycloadenosines have been measured in poly A irradiated with gamma rays in the absence of oxygen. High performance liquid chromatographic analysis of the nucleoside analogues obtained by hydrolysis of the irradiated poly A shows that the R isomer predominates to the extent of 2.5-fold at doses of ionizing radiation in the range of 0-400 Gy. |
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Authors:
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A F Fuciarelli; F Y Shum; J A Raleigh |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochemical and biophysical research communications Volume: 134 ISSN: 0006-291X ISO Abbreviation: Biochem. Biophys. Res. Commun. Publication Date: 1986 Jan |
Date Detail:
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Created Date: 1986-03-24 Completed Date: 1986-03-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372516 Medline TA: Biochem Biophys Res Commun Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 883-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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analogs & derivatives*,
analysis Chromatography, High Pressure Liquid Poly A / radiation effects* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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24937-83-5/Poly A; 58-61-7/Adenosine; 62475-47-2/8,5'-cycloadenosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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