Document Detail

Stepping-table gadolinium-enhanced digital subtraction MR angiography of the aorta and lower extremity arteries: preliminary experience.
MedLine Citation:
PMID:  10189454     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare stepping-table digital subtraction gadolinium-enhanced magnetic resonance (MR) angiography of the distal aorta and lower extremity arteries with conventional catheter digital subtraction x-ray angiography in patients with arterio-occlusive disease. MATERIALS AND METHODS: Twenty patients underwent both conventional catheter angiography and fast three-dimensional gadolinium-enhanced MR angiography of the aorta and outflow vessels at 1.5 T; the images were acquired in three consecutive imaging locations during a single infusion of a gadolinium chelate. RESULTS: Compared with catheter angiography, according to the findings of two blinded independent reviewers, MR angiography had sensitivities of 81% and 89% and specificities of 91% and 95%, respectively, for demonstration of insignificant (< or = 50%) stenosis versus significant (51%-100%) stenosis. For demonstration of occlusion, the sensitivity and specificity were 94% and 97%, respectively, by consensus. There was good interobserver correlation between the two readers overall (kappa = 0.65 for reporting the degree of narrowing in all lesions; 0.86, for reporting of insignificant versus significant stenoses; and 0.928, for reporting of occluded versus patient segments). CONCLUSION: Stepping-table digital subtraction contrast material-enhanced MR angiography has high accuracy compared with catheter angiography in patients with arterio-occlusive disease of the aorta and outflow vessels. These preliminary study results suggest that this technique may ultimately provide a safe, noninvasive, and cost-effective alternative to catheter angiography.
J F Meaney; J P Ridgway; S Chakraverty; I Robertson; D Kessel; A Radjenovic; M Kouwenhoven; A Kassner; M A Smith
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  211     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-04-19     Completed Date:  1999-04-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-67     Citation Subset:  AIM; IM    
Dept of Magnetic Resonance Imaging, Leeds General Infirmary, United Kingdom.
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MeSH Terms
Angiography, Digital Subtraction
Aorta, Abdominal
Aortic Diseases / diagnosis*
Arterial Occlusive Diseases / diagnosis*
Contrast Media
Gadolinium DTPA / diagnostic use
Image Processing, Computer-Assisted
Leg / blood supply
Magnetic Resonance Angiography / methods*
Observer Variation
Predictive Value of Tests
Sensitivity and Specificity
Subtraction Technique
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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