Document Detail


Stenting of aortic coarctation and exercise-induced hypertension in the young.
MedLine Citation:
PMID:  20095012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate whether the stenting of aortic coarctation enhance the risk of exercise-induced hypertension (EIH). BACKGROUND: There is the theoretical concern that aortic stents may cause increased aortic wall impedance and therefore systolic hypertension during exercise. METHODS: Blood pressure and the Doppler derived peak and mean systolic pressure gradient (PSG and MSG) across the distal aorta at the peak of exercise were evaluated in young patients (mean age 14 +/- 3 years) with aortic coarctation successfully treated with surgery or with stent implantation at least 1 year before the test. Only patients who reached the 85% maximal predicted heart rate or whose exercise test was interrupted because of severe hypertension, and in whom significant aortic narrowings were excluded by a MRI or a CT scan performed in the six months preceding the exercise test were included in the study. RESULTS: Seventeen patients formed the surgery-group, while 15 patients the stent-group. Patients in surgery-group were younger at coarctation repair and with a longer follow-up than those in stent-group. No difference was present regarding age, body surface area, gender, and presence, and degree of mildly hypoplastic aortic segments between the two groups as well as between patients with or without EIH. EIH was found in 35% of surgery-group patients and in 33% of stent-group patients. PSG and MSG were similar in the patients with or without EIH. CONCLUSIONS: EIH can be found in a high number of young patients successfully treated for aortic coarctation but at intermediate follow-up stent implantation does not seem to enhance the risk of EIH.
Authors:
Enrico De Caro; Isabella Spadoni; Roberto Crepaz; Michele Saitta; Gianluca Trocchio; Maria Grazia Calevo; Calevo Mg; Giacomo Pongiglione
Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  75     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-04-01     Revised Date:  2010-06-08    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  256-61     Citation Subset:  IM    
Affiliation:
Cardiovascular Department, Istituto Giannina Gaslini Children's Hospital, Genova, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Angioplasty, Balloon / adverse effects*,  instrumentation*
Aortic Coarctation / diagnosis,  physiopathology,  surgery,  therapy*
Aortography / methods
Blood Pressure
Child
Exercise*
Exercise Test
Female
Humans
Hypertension / diagnosis,  etiology*,  physiopathology
Italy
Magnetic Resonance Angiography
Male
Stents*
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography, Doppler
Vascular Surgical Procedures / adverse effects*
Young Adult
Comments/Corrections
Comment In:
Catheter Cardiovasc Interv. 2010 Feb 1;75(2):262   [PMID:  20095013 ]
Erratum In:
Catheter Cardiovasc Interv. 2010 Jun 1;75(7):1143
Note: Mg, Calevo [corrected to Calevo, Maria Grazia]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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