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Stent thrombosis is not always stent thrombosis: de novo atherosclerosis in a stented coronary segment.
MedLine Citation:
PMID:  19162351     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
We discuss a case of late thrombosis, 9 years after implantation of overlapping bare metal stents in a circumflex artery. The patient presented with an acute ST segment elevation infero-lateral myocardial infarction. The coronary angiogram revealed a sub-occlusive thrombus within the boundaries of the stents. Aspiration of the material was performed and pathological analysis showed, together with fibrin thrombus and platelet aggregates, fragments of an atherosclerotic plaque (parts of necrotic core with cholesterol clefts and inflammatory cells such as macrophages) including iron deposition, suggestive for plaque rupture. We conclude that this event occurred because of de novo atherosclerotic formation of a vulnerable, rupture-prone plaque within the boundaries of the stents.
Authors:
Pierfrancesco Agostoni; Paul Vermeersch; Michiel Knaapen; Stefan Verheye
Publication Detail:
Type:  Letter     Date:  2009-01-21
Journal Detail:
Title:  International journal of cardiology     Volume:  144     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e19-21     Citation Subset:  IM    
Copyright Information:
Copyright © 2008 Elsevier Ireland Ltd. All rights reserved.
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