| Stent grafting of dissected descending aorta in patients with Marfan's syndrome: mid-term results. | |
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MedLine Citation:
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PMID: 19463383 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study sought to assess the safety and the effectiveness of endovascular stent grafting of chronic aortic dissection (AD) in Marfan patients. BACKGROUND: The management of chronic AD of the descending thoracic aorta (DTA) is challenging. This is especially true in Marfan patients, who tend to exhibit poor short- and long-term results after conventional surgery. METHODS: Fifteen patients with Marfan's syndrome and chronic AD of the DTA were identified among the 457 patients of the European Talent Registry. All patients underwent endovascular treatment. RESULTS: No major adverse event was encountered during the procedure. Five patients experienced a primary endoleak (type 1, n = 4; type 2, n = 1). Three of them died, and 1 underwent successful conversion to open surgery. Five other patients experienced secondary endoleak (type 1, n = 4; type 3, n = 1). Four of them underwent successful conversion to either open or endovascular reintervention. Two other patients underwent successful conversion to open repair because of secondary aortic enlargement below the stent graft. After a mean follow-up of 2.1 +/- 1.4 years, 12 patients are alive. Of these 12, conversion to open repair was successfully performed in 5 patients. In the remaining 7 patients, complete thrombosis of the false lumen was achieved in 6 patients, with partial thrombosis in 1 patient. CONCLUSIONS: Endovascular stent grafting of the dissected DTA is feasible in selected Marfan patients with low mortality and morbidity rates. Nevertheless, the rate of primary and secondary endoleak is high. Close imaging surveillance is crucial to detect secondary aortic complications and to assess long-term results. |
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Authors:
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Bertrand Marcheix; Hervé Rousseau; Vanina Bongard; Robin H Heijmen; Christoph A Nienaber; Marek Ehrlich; Philippe Amabile; Jean-Paul Beregi; Rossela Fattori |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: JACC. Cardiovascular interventions Volume: 1 ISSN: 1876-7605 ISO Abbreviation: JACC Cardiovasc Interv Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-05-25 Completed Date: 2009-06-11 Revised Date: 2012-08-29 |
Medline Journal Info:
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Nlm Unique ID: 101467004 Medline TA: JACC Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 673-80 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Surgery, Rangueil University Hospital, Toulouse, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aneurysm, Dissecting / etiology, mortality, radiography, surgery* Aortic Aneurysm, Thoracic / etiology, mortality, radiography, surgery* Aortography / methods Blood Vessel Prosthesis* Blood Vessel Prosthesis Implantation / adverse effects, instrumentation*, mortality Chronic Disease Europe Feasibility Studies Female Humans Male Marfan Syndrome / complications*, mortality, radiography, surgery Middle Aged Prosthesis Failure Registries Reoperation Retrospective Studies Stents* Time Factors Tomography, X-Ray Computed Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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