| Stenosing ureteritis in a 7-year-old boy with Henoch-Schönlein purpura nephritis: A case report and review of the literature. | |
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MedLine Citation:
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PMID: 20382571 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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INTRODUCTION: Urinary tract obstruction resulting from Henoch-Schönlein purpura (HSP) is an extremely rare urologic entity. If the genitourinary system is involved, it is primarily in the form of a focal proliferative glomerulonephritis. Stenosing disease has received little attention in the literature and treatment options are limited. Despite early intervention renal loss may be inevitable. CASE REPORT: A 7-year-old African American male presented with renal failure secondary to bilateral sclerosing ureteritis 1 month after initial presentation with HSP. There was significant disease progression and he required multiple procedures, ultimately bilateral ureterocalycostomies and a left nephrectomy. DISCUSSION: HSP is an immune-mediated necrotizing vasculitis. It can affect any organ system; however, in the genitourinary system, focal proliferative glomerulonephritis is a common manifestation, occurring in 20-90% of cases [8]. Extrarenal manifestations are rare. CONCLUSION: Ureteritis and obstruction may be late occurrences, but should be considered in all patients presenting with a history of HSP and new-onset flank pain, acute renal failure, or anuria. Families and patients should be counseled that renal impairment may be a consequence of stenosing ureteritis. Management of these patients can be complicated but surgical correction must be considered in the treatment algorithm once the disease has stabilized. |
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Authors:
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Sean T Corbett; Jennifer N Lennington; Annabelle N Chua; Edmond T Gonzales |
Publication Detail:
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Type: Journal Article Date: 2010-04-10 |
Journal Detail:
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Title: Journal of pediatric urology Volume: 6 ISSN: 1873-4898 ISO Abbreviation: J Pediatr Urol Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-10-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101233150 Medline TA: J Pediatr Urol Country: England |
Other Details:
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Languages: eng Pagination: 538-42 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA. stc2u@virginia.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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