| Stem cells and the vasculature. | |
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MedLine Citation:
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PMID: 22064433 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Unraveling the contribution of stem and progenitor cells to blood vessel formation and, reciprocally, the importance of blood vessels to the production and function of stem and progenitor cells, has been a major focus of vascular research over the last decade, but has spawned many controversies. Here I review how vascular stem and progenitor cells contribute both vascular and nonvascular cells during development and in disease, and how nonvascular stem and progenitor cells might contribute to vascular lineages. I also discuss the role of the vasculature in forming stem and progenitor cell niches. Finally, I highlight the potential relevance of these relationships to disease etiology and treatment. |
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Authors:
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Victoria L Bautch |
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Publication Detail:
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Type: Journal Article Date: 2011-11-07 |
Journal Detail:
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Title: Nature medicine Volume: 17 ISSN: 1546-170X ISO Abbreviation: Nat. Med. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9502015 Medline TA: Nat Med Country: United States |
Other Details:
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Languages: eng Pagination: 1437-43 Citation Subset: IM |
Affiliation:
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1] Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [3] Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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