Document Detail

Stem cells for kidney repair: useful tool for acute renal failure?
MedLine Citation:
PMID:  18794815     Owner:  NLM     Status:  MEDLINE    
Several cell types isolated from adult tissues have been reported to differentiate into mature kidney cells that may participate in renal repair after systemic administration. Chen et al. report that local mesenchymal stem cells derived from adult mouse kidneys are another source of cells with similar properties. Although these cells have the potential to differentiate into endothelial-lineage cell types, their therapeutic benefit to the ischemic kidney is mainly via the production of renoprotective factors.
Takashi Yokoo; Tetsuya Kawamura; Eiji Kobayashi
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Publication Detail:
Type:  Comment; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Kidney international     Volume:  74     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-16     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  847-9     Citation Subset:  IM    
Project Laboratory for Kidney Regeneration, Division of Nephrology and Hypertension, Department of Internal Medicine, Institute of DNA Medicine, Jikei University School of Medicine, Tokyo, Japan.
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MeSH Terms
Kidney Failure, Acute / pathology,  therapy*
Kidney Tubules / pathology
Regenerative Medicine / methods
Stem Cell Transplantation / methods*
Stem Cells / cytology,  physiology
Comment On:
Kidney Int. 2008 Oct;74(7):879-89   [PMID:  18596729 ]

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