Document Detail


Stem cells for enhancing recovery after stroke: a review.
MedLine Citation:
PMID:  19383051     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke have been performed. Trials are also underway evaluating haematopoietic precursors mobilised with granulocyte-colony stimulating factor, an approach offering an autologous means of administrating stem cells for therapeutic purposes. This review summarises current knowledge in regard to stem cells and their potential for helping improve recovery after stroke.
Authors:
Tim England; Paul Martin; Philip M W Bath
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  International journal of stroke : official journal of the International Stroke Society     Volume:  4     ISSN:  1747-4949     ISO Abbreviation:  -     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-22     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101274068     Medline TA:  Int J Stroke     Country:  England    
Other Details:
Languages:  eng     Pagination:  101-10     Citation Subset:  IM    
Affiliation:
Stroke Trials Unit, Institute of Neuroscience, University of Nottingham, Nottingham, UK.
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MeSH Terms
Descriptor/Qualifier:
Animals
Clinical Trials as Topic
Humans
Stem Cell Transplantation / methods*
Stem Cells / physiology*
Stroke / therapy*
Grant Support
ID/Acronym/Agency:
//Medical Research Council

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