| Status of liposomes as MR contrast agents. | |
| | |
MedLine Citation:
|
PMID: 8428087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Recent work on the development of liposomal magnetic resonance (MR) contrast agents has yielded structures with higher overall relaxivity than that of other nanoparticles of similar diameter. Liposomes incorporating membrane-bound complexes of manganase ("memsomes") produce greater hepatic enhancement per micromole of metal ion than either ferrite particles or paramagnetic chelates. Memsomes also hold promise for targeting of sites outside the liver. Work is in progress to take these agents into clinical trials. |
| | |
Authors:
|
E C Unger; D K Shen; T A Fritz |
Related Documents
:
|
3807887 - Mechanism of the selective toxicity of amphotericin b incorporated into liposomes. 18359207 - Membrane interactions of ternary phospholipid/cholesterol bilayers and encapsulation ef... 3443287 - Effects of some cyclic elements containing amphiphilic compounds on stability and trans... 9247167 - Combination of antitumor ether lipid with lipids of complementary molecular shape reduc... 21367197 - 214 effect of long-distance transportation of ovaries on the development of in vitro-ma... 15889467 - Freeze-drying process design by manometric temperature measurement: design of a smart f... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 3 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 1993 Jan-Feb |
Date Detail:
|
Created Date: 1993-03-09 Completed Date: 1993-03-09 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 195-8 Citation Subset: IM |
Affiliation:
|
Department of Radiology, University of Arizona Health Sciences Center, Tucson 85724. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Contrast Media* Gadolinium / diagnostic use Humans Liposomes / diagnostic use* Liver / anatomy & histology* Liver Neoplasms, Experimental / diagnosis Magnetic Resonance Imaging* Manganese / diagnostic use |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Liposomes; 7439-96-5/Manganese; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Proton relaxation enhancement.
Next Document: Dual effects of gadodiamide injection in depiction of the region of myocardial ischemia.