Document Detail


Status epilepticus caused by a myxoedema coma.
MedLine Citation:
PMID:  16788220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a 63-year-old woman who presented with status epilepticus, coma and hypoventilation is reported. A primary neurological cause was considered. Hypothermia led to further investigations and a diagnosis of severe hypothyroidism. The neurological complications of hyperthyriodism include alteration in mental status with slowness, decreased concentration and lethargy, headache, cranial nerve palsies, dysarthria, hoarseness, myopathy, neuropathy, reflex changes, ataxia, and psychotic episodes. Our patient suffered from a rare consequence of severe hypothyroidism presenting with status epilepticus and she died despite treatment. To our knowledge this is the second patient to be reported with myxoedema coma with this kind of presentation. Despite therapeutic options, there is a high mortality rate.
Authors:
H J Jansen; S R Oedit Doebé; E S Louwerse; J C van der Linden; P M Netten
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Netherlands journal of medicine     Volume:  64     ISSN:  0300-2977     ISO Abbreviation:  Neth J Med     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-21     Completed Date:  2006-07-27     Revised Date:  2007-01-30    
Medline Journal Info:
Nlm Unique ID:  0356133     Medline TA:  Neth J Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  202-5     Citation Subset:  IM    
Affiliation:
Department of Intensive Care, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands. Henry_jansen@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Atrophy / pathology*
Coma / complications*
Fatal Outcome
Female
Glasgow Coma Scale
Humans
Hypothyroidism / complications*,  drug therapy*
Middle Aged
Myxedema / complications*
Respiratory Tract Diseases / etiology
Status Epilepticus / etiology*
Thyroid Gland / pathology*
Thyroxine / therapeutic use*
Chemical
Reg. No./Substance:
7488-70-2/Thyroxine
Comments/Corrections
Comment In:
Neth J Med. 2006 Nov;64(10):387; author reply 387-8   [PMID:  17122458 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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