| Statistical issues in carcinogenic risk assessment. | |
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MedLine Citation:
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PMID: 2050065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Considerable progress has been made on the development of a variety of analytical methods to aid in the carcinogenic risk associated with exposure to both occupational and environmental agents. Although the development of these methods has been accompanied by consideration of many statistical issues, there are many areas where additional effort could be directed if these analytical methods are to provide the most appropriate interpretation of risk. These issues include methods of combining multiple studies to obtain an overall risk estimate, the robustness of the statistical model, methods of selection among competing models, an assessment of the effect of different measures of exposure on the estimated dose-response relationship, and development of surveillance methodology. These issues are discussed, and productive areas of future research are indicated. |
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Authors:
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H E Rockette |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Environmental health perspectives Volume: 90 ISSN: 0091-6765 ISO Abbreviation: Environ. Health Perspect. Publication Date: 1991 Jan |
Date Detail:
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Created Date: 1991-07-25 Completed Date: 1991-07-25 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0330411 Medline TA: Environ Health Perspect Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 223-7 Citation Subset: IM |
Affiliation:
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Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carcinogens, Environmental* Data Interpretation, Statistical Humans Mass Screening Models, Statistical* Neoplasms / chemically induced*, diagnosis Risk |
| Chemical | |
Reg. No./Substance:
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0/Carcinogens, Environmental |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): Environ Health Perspect ISSN: 0091-6765 |
Article Information Download PDF  Print publication date: Month: 1 Year: 1991 Volume: 90First Page: 223 Last Page: 227 ID: 1519477 PubMed Id: 2050065 |
| Statistical issues in carcinogenic risk assessment. | |
| H E Rockette | |
| Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261. |
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