Document Detail

Statistical issues in carcinogenic risk assessment.
Jump to Full Text
MedLine Citation:
PMID:  2050065     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Considerable progress has been made on the development of a variety of analytical methods to aid in the carcinogenic risk associated with exposure to both occupational and environmental agents. Although the development of these methods has been accompanied by consideration of many statistical issues, there are many areas where additional effort could be directed if these analytical methods are to provide the most appropriate interpretation of risk. These issues include methods of combining multiple studies to obtain an overall risk estimate, the robustness of the statistical model, methods of selection among competing models, an assessment of the effect of different measures of exposure on the estimated dose-response relationship, and development of surveillance methodology. These issues are discussed, and productive areas of future research are indicated.
Authors:
H E Rockette
Related Documents :
16544815 - A scaled sample space cube used to illustrate attributable fractions.
11217705 - Development and initial experience with the new "exposure database of the federal states".
18501955 - Florida red tide and human health: a pilot beach conditions reporting system to minimiz...
15986055 - Field test results of an automated exposure assessment tool, the local positioning syst...
20513665 - Slims--a user-friendly sample operations and inventory management system for genotyping...
22138825 - Bayesian localization microscopy reveals nanoscale podosome dynamics.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental health perspectives     Volume:  90     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-07-25     Completed Date:  1991-07-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-7     Citation Subset:  IM    
Affiliation:
Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Carcinogens, Environmental*
Data Interpretation, Statistical
Humans
Mass Screening
Models, Statistical*
Neoplasms / chemically induced*,  diagnosis
Risk
Chemical
Reg. No./Substance:
0/Carcinogens, Environmental
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
Download PDF

Print publication date: Month: 1 Year: 1991
Volume: 90First Page: 223 Last Page: 227
ID: 1519477
PubMed Id: 2050065

Statistical issues in carcinogenic risk assessment.
H E Rockette
Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA 15261.



Article Categories:
  • Research Article


Previous Document:  Assessing, accommodating, and interpreting the influences of heterogeneity.
Next Document:  Use of biological markers and pharmacokinetics in human health risk assessment.