Document Detail

Statins for progression of aortic valve stenosis and the best evidence for making decisions in health care.
MedLine Citation:
PMID:  21437508     Owner:  NLM     Status:  In-Data-Review    
In the Western world, calcified aortic valve stenosis is the most common form of valvular heart disease, affecting up to 3% of adults over the age of 75 years. It is a gradually progressive disease, characterized by a long asymptomatic phase that may last for several decades, followed by a short symptomatic phase associated with severe restriction of the valve orifice. Investigations on treatments for aortic valve stenosis are still in progress. Thus, it is believed that calcification of aortic valve stenosis is similar to the process of atherosclerosis that occurs in coronary artery disease. Recent studies have suggested that cholesterol lowering through the use of statins may have a salutary effect on the progression of aortic valve stenosis.
Luciana Thiago; Selma Rumiko Tsuj; Alvaro Nagib Atallah; Maria Eduarda Dos Santos Puga; Aécio Flávio Teixeira de Góis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  São Paulo medical journal = Revista paulista de medicina     Volume:  129     ISSN:  1806-9460     ISO Abbreviation:  Sao Paulo Med J     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-03-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897261     Medline TA:  Sao Paulo Med J     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  41-5     Citation Subset:  IM    
Faculdade de Medicina de Marília.
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