| Statins as anti-arrhythmics: a systematic review part II: effects on risk of ventricular arrhythmias. | |
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MedLine Citation:
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PMID: 19816987 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Recent studies have demonstrated that statins may possess anti-arrhythmic properties in addition to their lipid-lowering effects. METHODS: Studies which reported the association of statins with the incidence of ventricular arrhythmias were identified through a systematic review of the published literature. RESULTS: Statins have been associated with a significant reductions in ventricular arrhythmia in cardiomyopathy patients with an implantable cardioverter defibrillator, although randomized trials have not been completed. CONCLUSIONS: Published data suggests that statins may possess anti-arrhythmic properties that reduce the propensity for ventricular arrhythmias. Most of this data is observational; more randomized, placebo-controlled trials are needed. |
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Authors:
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Hussam Abuissa; James H O'Keefe; Kevin A Bybee |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical cardiology Volume: 32 ISSN: 1932-8737 ISO Abbreviation: Clin Cardiol Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-11-20 Completed Date: 2010-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 549-52 Citation Subset: IM |
Affiliation:
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University of Missouri, Kansas City, Missouri, USA. abuissa.hussam@mayo.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Arrhythmia Agents
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therapeutic use* Arrhythmias, Cardiac / etiology, prevention & control* Combined Modality Therapy Death, Sudden, Cardiac / etiology, prevention & control Defibrillators, Implantable* Evidence-Based Medicine Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use* Recurrence / prevention & control Risk Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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