| Statins and ischaemia reperfusion injury: a molecular biological review. | |
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MedLine Citation:
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PMID: 19485917 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect. |
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Authors:
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M N A Abdul Rahman; I C Chetter |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current vascular pharmacology Volume: 8 ISSN: 1875-6212 ISO Abbreviation: Curr Vasc Pharmacol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-09-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101157208 Medline TA: Curr Vasc Pharmacol Country: United Arab Emirates |
Other Details:
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Languages: eng Pagination: 831-5 Citation Subset: IM |
Affiliation:
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Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, UK. hishami.abdulrahman@hey.nhs.uk |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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