| Statin therapy and contrast-induced nephropathy after primary angioplasty. | |
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MedLine Citation:
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PMID: 18466989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A recent study suggested that statin therapy may prevent contrast-induced nephropathy (CIN) following primary angioplasty. Our aim was to assess the effect of statins in this setting in a larger population. We evaluated 589 consecutive patients with acute myocardial infarction who underwent primary angioplasty at our institution. Contrast-induced nephropathy was defined as an increase in serum creatinine by > or =0.5 mg/dL within 72 h following the procedure. Overall, 69 patients (11.9%) developed CIN. The incidence of CIN in the group on statins was 15.9%, as compared with 10.8% in the group not taking statins (p=0.2). Thus, we did not observe a protective effect of statin therapy on CIN development after primary angioplasty. |
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Authors:
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Alberto Bouzas-Mosquera; Jos? M V?zquez-Rodr?guez; Ram?n Calvi?o-Santos; Nicol?s V?zquez-Gonz?lez; Alfonso Castro-Beiras |
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Publication Detail:
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Type: Comment; Letter Date: 2008-05-07 |
Journal Detail:
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Title: International journal of cardiology Volume: 134 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-11 Completed Date: 2010-02-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 430-1 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary*
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adverse effects Contrast Media / adverse effects* Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use* Kidney Failure, Acute / chemically induced*, drug therapy*, prevention & control Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
| Comments/Corrections | |
Comment On:
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Int J Cardiol. 2008 Jun 6;126(3):435-6
[PMID:
17462753
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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