| Statin-fibrate combination for mixed dyslipidaemia: a limited option? | |
| | |
MedLine Citation:
|
PMID: 20662560 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Abstract A growing body of evidence suggests that targeting low-density lipoprotein cholesterol is not enough and that a substantial residual risk remains despite aggressive statin treatment, particularly in patients with mixed dyslipidemia. Statin plus fibrate combination results in a more effective control of several lipid parameters than either monotherapy with a safety profile similar to both monotherapies. Therefore, this combination might represent a therapeutic option for selected patients with mixed dyslipidemia. However, the clinical benefit of statin/fibrate combination has only been observed in small subgroup analyses and more data are needed before a wider implementation is recommended in everyday clinical practice. |
| | |
Authors:
|
Vasilios G Athyros; Konstantinos Tziomalos; Asterios Karagiannis; Dimitri P Mikhailidis |
Publication Detail:
|
Type: Comment; Editorial |
Journal Detail:
|
Title: Current medical research and opinion Volume: 26 ISSN: 1473-4877 ISO Abbreviation: Curr Med Res Opin Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-16 Completed Date: 2010-12-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0351014 Medline TA: Curr Med Res Opin Country: England |
Other Details:
|
Languages: eng Pagination: 2137-40 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Choice Behavior Drug Combinations Dyslipidemias / drug therapy* Fibric Acids / administration & dosage*, adverse effects Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*, adverse effects Hypolipidemic Agents / administration & dosage, adverse effects |
| Chemical | |
Reg. No./Substance:
|
0/Drug Combinations; 0/Fibric Acids; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Hypolipidemic Agents |
| Comments/Corrections | |
Comment On:
|
Curr Med Res Opin. 2010 Sep;26(9):2141-6
[PMID:
20662558
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Serum uric acid and self-reported rheumatoid arthritis in a multiethnic adult female population.
Next Document: Association analysis of the poliovirus receptor related-2 gene in patients with nonsyndromic cleft l...