| Statin therapy--Part II: Clinical considerations for cardiovascular disease. | |
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MedLine Citation:
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PMID: 20547576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, commonly known as statins, are the medical treatment of choice for hypercholesterolemia. In addition to achieving a therapeutic decrease in serum cholesterol levels, statin therapy appears to promote pleiotropic effects that are independent of changes in serum cholesterol. These cholesterol lowering and pleiotropic effects are beneficial not only for the coronary circulation, but for the myocardium and peripheral arterial system as well. Patients receiving statin therapy must be carefully monitored, however, as statins potentially have harmful side effects and drug interactions. This article is part II of a 2-part review, and it focuses on the clinical aspects of statin therapy in cardiovascular disease. |
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Authors:
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Benjamin Sadowitz; Keri Seymour; Michael J Costanza; Vivian Gahtan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review Date: 2010-06-14 |
Journal Detail:
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Title: Vascular and endovascular surgery Volume: 44 ISSN: 1938-9116 ISO Abbreviation: Vasc Endovascular Surg Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-09-16 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136421 Medline TA: Vasc Endovascular Surg Country: United States |
Other Details:
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Languages: eng Pagination: 421-33 Citation Subset: IM |
Affiliation:
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Division of Vascular Surgery and Endovascular Services, SUNY Upstate Medical University, Syracuse, NY 13210, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Diseases
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drug therapy Cardiovascular Diseases / drug therapy* Cerebrovascular Disorders / drug therapy Coronary Artery Disease / drug therapy Drug Interactions Heart Failure / drug therapy Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects, therapeutic use* Peripheral Arterial Disease / drug therapy Risk Assessment Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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